Characteristic | Details |
---|---|
Generic Name | Glipizide and Metformin |
Dosage Forms | Tablets: 2.5 mg/250 mg, 2.5 mg/500 mg |
Primary Use | Type 2 Diabetes Mellitus Management |
Mechanism | Stimulates Insulin Secretion, Decreases Hepatic Glucose Production |
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Glipizide and Metformin in Metaglip regulate blood sugar levels. Take it orally with meals. This minimizes gastrointestinal discomfort. The standard initial dose is 2.5 mg/250 mg once daily. Adjust based on individual response and glycemic goals. Swallow tablets whole. Avoid crushing or chewing.
A physician may recommend titration for better control. Monitor glucose regularly. Consistency in timing enhances effectiveness. Consult healthcare providers for personalized schedules.
Diet and exercise significantly impact Metaglip efficacy. Maintain a balanced diet. Regular physical activity complements treatment. Follow professional guidance.
The typical adult starting dose is 2.5 mg/250 mg once daily. Increase cautiously by 2.5 mg/500 mg weekly based on tolerance. Maximum recommended dose reaches 10 mg/2000 mg daily. Adjustments reflect patient-specific needs and tolerances.
Elderly patients require special consideration. Renal function influences dosage adjustments. Regular assessment ensures optimal dosing and minimizes risk.
Monitor for lactic acidosis, especially in patients with renal impairment. Symptoms include malaise, respiratory distress, and somnolence. Discontinue Metaglip in such cases.
Be vigilant for hypoglycemia risks. Adjust insulin or sulfonylurea doses accordingly. Recognize signs of hypoglycemia: tremors, confusion, or dizziness.
Regular laboratory tests assess renal and hepatic functions. Ensure patient compliance and monitor therapy efficacy.
Metaglip is contraindicated in pregnancy due to potential risks to the fetus. Transition to insulin therapy if necessary during pregnancy. Discuss pregnancy plans with healthcare providers for appropriate management strategies.
It is unknown if Metaglip components pass into breast milk. Caution is advised. Weigh benefits against potential risks to the infant.
Common adverse reactions include gastrointestinal upset, diarrhea, and nausea. These typically resolve with continued use. Gradual dose escalation mitigates these effects.
Serious effects such as lactic acidosis warrant immediate medical attention. This rare condition requires urgent care. Symptoms include muscle pain, dizziness, and cold extremities.
Metaglip is not available over the counter. Prescription by a healthcare professional is necessary. This ensures safe and appropriate use tailored to individual needs.
Adherence to prescription guidelines is critical. Periodic evaluation by healthcare providers ensures therapeutic effectiveness and safety.
Component | Metaglip Dosage |
---|---|
Glipizide | 2.5 mg |
Metformin | 250 mg |
More comprehensive details are accessible on NCBI’s website, a resource for scientific literature.